Cisco Secure Endpoint vs Malwarebytes ThreatDown (2026)

Our verdict

Cisco Secure Endpoint vs Malwarebytes ThreatDown: on our data-weighted scoring, Malwarebytes ThreatDown edges ahead (8.1 vs 7.9/10). Cisco Secure Endpoint starts at Custom quote and is best for cisco-centric enterprises wanting integrated edr; Malwarebytes ThreatDown starts at $69/endpoint/yr and is best for smbs/msps wanting simple, effective edr with optional mdr. Choose Malwarebytes ThreatDown for the stronger overall track record; consider Cisco Secure Endpoint if its pricing model or fit matches your environment better. Side-by-side table below.

Cisco Secure Endpoint vs Malwarebytes ThreatDown — head-to-head
Cisco Secure EndpointMalwarebytes ThreatDown
Starting price Custom quote $69/endpoint/yr
Pricing model quote per endpoint
Free trial / tier yes yes
Best for Cisco-centric enterprises wanting integrated EDR SMBs/MSPs wanting simple, effective EDR with optional MDR
Deployment Cloud Cloud
G2 rating 4.4/5 (150) 4.6/5 (900)
Capterra rating
Our score 7.9/10 8.1/10

Cisco Secure Endpoint

Pros

  • Talos threat intelligence
  • Integrates with Cisco stack
  • Solid detection

Cons

  • Best within Cisco ecosystem
  • Quote pricing
  • Heavier admin

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Affiliate link: Cisco Secure Endpoint may pay us a commission if you sign up through this link. It never affects our data-driven ranking.

Malwarebytes ThreatDown

Pros

  • Easy to deploy and use
  • Great remediation heritage
  • Transparent entry price

Cons

  • Advanced features need higher tiers
  • Reporting basic
  • Newer to EDR

Visit Malwarebytes ThreatDown →

Affiliate link: Malwarebytes ThreatDown may pay us a commission if you sign up through this link. It never affects our data-driven ranking.

Choose Cisco Secure Endpoint if…

You need cisco-centric enterprises wanting integrated edr. See the Cisco Secure Endpoint pricing and review.

Choose Malwarebytes ThreatDown if…

You need smbs/msps wanting simple, effective edr with optional mdr. See the Malwarebytes ThreatDown pricing and review.

In depth

Pricing: Malwarebytes ThreatDown vs Cisco Secure Endpoint

Malwarebytes ThreatDown bills on a per endpoint model from $69/endpoint/yr (yes trial), while Cisco Secure Endpoint uses a quote model from Custom quote (yes trial). Because the models differ, the cheaper option flips depending on your fleet size — model both at your seat/endpoint count.

Features & deployment

Malwarebytes ThreatDown ships 5 headline capabilities (Strong remediation engine, EDR + ransomware rollback, Simple console, Optional MDR) and deploys Cloud. Cisco Secure Endpoint ships 4 (EDR with Talos intel, SecureX/XDR integration, Threat hunting, Sandboxing), deploying Cloud.

Ratings & verdict

Malwarebytes ThreatDown holds 4.6/5 (900 G2 reviews); Cisco Secure Endpoint holds 4.4/5 (150 G2 reviews). On our data-weighted score, Malwarebytes ThreatDown edges ahead (8.1 vs 7.9/10). Pick Cisco Secure Endpoint instead when cisco-centric enterprises wanting integrated edr. See Malwarebytes ThreatDown alternatives or Cisco Secure Endpoint alternatives.

Frequently asked questions

Cisco Secure Endpoint vs Malwarebytes ThreatDown: which is better?
Cisco Secure Endpoint vs Malwarebytes ThreatDown: on our data-weighted scoring, Malwarebytes ThreatDown edges ahead (8.1 vs 7.9/10). Cisco Secure Endpoint starts at Custom quote and is best for cisco-centric enterprises wanting integrated edr; Malwarebytes ThreatDown starts at $69/endpoint/yr and is best for smbs/msps wanting simple, effective edr with optional mdr.
Is Cisco Secure Endpoint cheaper than Malwarebytes ThreatDown?
Cisco Secure Endpoint starts at Custom quote and Malwarebytes ThreatDown starts at $69/endpoint/yr (see the pricing rows for models and limits).
Data as of June 16, 2026. Sources: cisco.com, threatdown.com. Figures are pulled from public vendor and security data and refreshed automatically.